Description

OXYGENSLAB ORLISTAT(120MG/CAPSULE=60 CAPSULES)

XENICAL (Orlistat) is a gastrointestinal lipase inhibitor for obesity management that acts by inhibiting the absorption of dietary fats.

DOSAGE AND ADMINISTRATION

Recommended Dosing

The recommended dose of XENICAL is one 120-mg capsule three times a day with each main meal containing fat (during or up to 1 hour after the meal).

The patient should be on a nutritionally balanced, reduced-calorie diet that contains approximately 30% of calories from fat. The daily intake of fat, carbohydrate, and protein should be distributed over three main meals. If a meal is occasionally missed or contains no fat, the dose of XENICAL can be omitted.

Because XENICAL has been shown to reduce the absorption of some fat-soluble vitamins and betacarotene, patients should be counseled to take a multivitamin containing fat-soluble vitamins to ensure adequate nutrition [see WARNINGS AND PRECAUTIONS]. The vitamin supplement should be taken at least 2 hours before or after the administration of XENICAL, such as at bedtime.

For patients receiving both XENICAL and cyclosporine therapy, administer cyclosporine 3 hours after XENICAL.

For patients receiving both XENICAL and levothyroxine therapy, administer levothyroxine and XENICAL at least 4 hours apart. Patients treated concomitantly with XENICAL and levothyroxine should be monitored for changes in thyroid function.

Doses above 120 mg three times a day have not been shown to provide additional benefit.

Based on fecal fat measurements, the effect of XENICAL is seen as soon as 24 to 48 hours after dosing. Upon discontinuation of therapy, fecal fat content usually returns to pretreatment levels within 48 to 72 hours.

When Shouldn’t I Take Orlistat ?

Always tell your doctor about all the medications you’re taking. Orlistat can interact with certain drugs, affecting their levels or how they work in your body, which could lead to life-threatening consequences. Check with your doctor if you’re taking warfarin (a blood thinner), diabetes or thyroid medications, or other weight loss drugs. In some cases, your dosages may need to be adjusted.

Don’t take Orlistat if:

• You’ve had an organ transplant. Alli is known to interfere with drugs used to prevent transplant rejection.
• You’re taking cyclosporine.
• You’re not overweight.
• You’re pregnant or breastfeeding.

 

Side Effects of Orlistat

Loose stools and other bowel movement changes are the most common side effects of Orlistat. Symptoms typically occur during the first few weeks of treatment and then go away. However, they may continue.

Tell your doctor if you have any of the following symptoms and they become severe or do not go away:

• Difficulty controlling bowel movements
• Loose, frequent stools
• Oily or fatty stools
• Oily spots on undergarments
• Stomach or rectum pain
• Passing gas more often
• Urgent need to have a bowel movement
• Anxiety
• Changes in your menstrual cycle
• Headaches

Emergency Side Effects of Orlistat

Call your doctor immediately if you develop any of these symptoms:

• Difficulty breathing
• Difficulty swallowing
• Hives or itching
• Stomach pain that is severe or does not go away